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KMID : 0368820060450050468
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Journal of the Korean Neuropsychiatr Association
2006 Volume.45 No. 5 p.468 ~ p.475
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Temperament and Genetic Polymorphism in Korean Male Adolescents with Internet Addiction Tendency
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Kim Eun-Young
Han Doug-Hyun
Lee Young-Sik
Suh Dong-Soo
Kee Baik-Seok
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Abstract
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Objective: Among chemical and non-chemical dependence, internet addiction is one of the most frequent addictive behavior in adolescent. This study was performed to detect certain temperamental and genetic characteristics in adolescent with internet addiction tendency.
Methods: 87 adolescents with internet addiction tendency (AIT) and 78 adolescents without internet addiction tendency (NAIT) were classified by Young’s Internet Addiction Test. Cloninger’s Temperament Character Inventory and 6 candidate genes of drug addiction (DRD2 TaqI A, DRD4, DAT1, 5-HTTLPR, NET-8, and COMT) polymorphisms were tested between two groups.
Results: Novelty Seeking scores (p=0.001) and Harm Avoidance scores (p=0.042) were significantly higher in AIT. The frequency of DRD2-A1/A1 genotype and G allele of NET-8 in AIT was higher than that in NAIT. In AIT, Novelty Seeking scores were significantly different (p=0.011) according to NET-8 genotypes (G/G>G/A>A/A).
Conclusion: These data suggest that male adolescents with internet addiction tendency have the specific temperament and genetic polymorphisms like chemical dependence.
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KEYWORD
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Internet Addiction Tendency, Male Adolescent, Temperament, Genetic Polymorphism
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